The aim of this paper is to show that, despite what may appear, the hedonism defended by La Mettrie in the Discours sur le bonheur does not imply neither a rejection of moral values nor an attempt to undermine social bonds. In other words, the text highlights the boundaries of individual happiness in the work of the doctor of Saint–Malo. This, on the other hand, sheds some light on the problematic link between philosophy, medicine and politics in La Mettrie’s works.