The aim of this paper is (i) to make explicit the importance and necessity of creating spaces of mediation in the educational field between humanistic and scientific cultures, and (ii) to point out the concrete possibility of finding a convergence zone in History and Philosophy of Science. The pursuit for mediation fields of knowledge between these two cultures is not a trivial matter: science is a fundamental structural element of our societies and, therefore, a better understanding of this phenomenon and its relationship with the humanities will have a positive impact on its integration and development within current democracies.